Healthcare providers recognize Ibogaine primarily for its unique ability to reduce in large part drug withdrawal symptoms. Ibogaine treatment allows people who are addicted to detox with greater efficacy.

Effects of Various Dosages

Iboga effects are apparently dependent directly on the dosage. Low doses are helpful for increasing endurance and muscle strength. Indigenous African tribes use them as aphrodisiacs. They also increase their endurance and mental alertness when they are hunting.
High doses of ibogaine induce often-vivid psychedelic effects. Users have reported a dream state without losing consciousness. Larger doses do induce hallucinations, but conventional users avoid this size dose since it is close to the toxic levels of the drug. Apprehension and anxiety often accompany these hallucinations.

Ibogaine Therapy for Drug Addiction

The initial investigation into ibogaine was fueled by reports of addicts who treated themselves with the drug, and these people experienced virtually no desire to continue abusing opiates after ibogaine treatment. Since these reports, researchers are studying 18-methoxycoronaridine and ibogaine for useful drug addiction treatment.

One ibogaine dose has caused noribogaine levels in the blood to remain at an elevated level for a full day. This partially explains the lengthy duration of the drug’s action. Ibogaine is stored in body fat and slowly released from there.
Ibogaine pharmacology is quite complex and is believed to have multiple actions. Researchers have seen this reflected in the effectiveness of ibogaine therapy for various addictions. It reacts to several systems of neurotransmitters in the human brain. This possibly contributes to the assistance it gives people who abuse opiates when they go through detox.

Noribogaine is responsible for elevated brain serotonin concentrations, which may explain its effects as an anti-depressant. Sustained noribogaine presence in the central nervous system may help in producing the self-tapering effect for opiate-dependent patients after they abruptly discontinue the use of opiates. Researchers are studying ibogaine treatment for use against other diseases. Among them are Alzheimer’s, depression, PTSD, and bipolar disorder. Since it is classified as a controlled substance in the United States, it is not generally available for use in any of its possible applications, without being prescribed by a physician.